CMV IgM Rapid Test Uncut Sheet

CMV IgM Rapid Test

Type: Uncut Sheet

Brand: Bio-mapper

Catalog: RT0211

Specimen: WB/S/P

Sensitivity: 92.70%

Specificity: 99.10%

Cytomegalovirus (CMV) is a kind of opportunistic pathogenic virus, which is ubiquitous in nature. In addition to infecting human fibroblasts, human cytomegalovirus can also infect endothelial cells, sperm cells, epidermal cells, macrophages, etc., causing cytomegalovirus infection, hepatitis, retinitis, post transfusion infectious mononucleosis and other diseases. In addition, human cytomegalovirus infection in pregnant women and children is relatively serious, which is an important factor causing birth defects and various irreversible injuries. Once people are infected with cytomegalovirus, they will carry it for life. When the latent virus is activated by some inducement, it can cause obvious clinical symptoms. The items commonly used for CMV serological detection include IgG and IgM antibody detection. IgM detection is an effective indicator to diagnose whether CMV is an active infection or a recent infection.

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Cytomegalovirus infection is very common among people, but most of them are subclinical recessive and latent infections. When the infected person has low immunity or is pregnant, receives immunosuppressive treatment, organ transplantation, or suffers from cancer, the virus can be activated to cause clinical symptoms. After human cytomegalovirus infects pregnant women, the virus infects the fetus through the placenta, causing intrauterine infection. Therefore, the detection of CMV IgM antibody is of great significance for understanding the cytomegalovirus infection of women of childbearing age, early diagnosis of congenital human cytomegalovirus infection and prevention of birth of congenital infected children.
It is reported that 60%~90% of adults can detect IgG like CMV antibodies, and anti CMV IgM and IgA in serum are markers of virus replication and early infection. CMV IgG titer ≥ 1 ∶ 16 is positive, indicating that CMV infection continues. The increase of IgG antibody titer of double sera by 4 times or more indicates that CMV infection is recent. CMV IgM positive indicates recent cytomegalovirus infection.