HSV-II IgM Rapid Test Uncut Sheet

HSV-II IgM Rapid Test uncut sheet:

Type: Uncut Sheet

Brand: Bio-mapper

Catalog: RT0411

Specimen: WB/S/P

Sensitivity: 90.20%

Specificity: 99.10%

Herpes simplex virus (HSV) is a kind of common pathogen that seriously endangers human health and causes skin diseases and venereal diseases. The virus is divided into two serotypes: herpes simplex virus type I (HSV-1) and herpes simplex virus type II (HSV-2). HSV-2 mainly causes infection in the lower part of the waist (such as genitals, anus, etc.), which is mainly transmitted through direct close contact and sexual contact. The latent site of the virus is the sacral ganglion. After stimulation, the latent virus can be activated, causing recurrent infection. Pregnant women infected with HSV can cause abortion, stillbirth and perinatal infection of newborns. The clinical diagnosis of HSV infection mainly depends on laboratory diagnostic techniques. After HSV infection, the body will be stimulated to produce immune response. First, IgM antibody will be produced, and then IgG antibody will be produced. In clinical practice, ELISA is often used to detect the IgM and IgG antibody levels of HSV in serum.

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The positive person indicates that the possibility of herpes simplex virus type II infection in the near future is high. Genital herpes is mainly caused by HSV-2 infection, which is one of the common sexually transmitted diseases. Typical skin lesions are blisters, pustules, ulcers and erosions at the genital area. Serological antibody test (including IgM antibody and IgG antibody test) has a certain sensitivity and specificity, which is not only applicable to patients with symptoms, but also can detect patients without skin lesions and symptoms.
IgM exists in the form of pentamer, and its relative molecular weight is large. It is not easy to pass through the blood-brain barrier and placental barrier. It first appears after the human body is infected with HSV, and it can last for about 8 weeks. However, the antibody is often not found in patients with latent infection and asymptomatic patients.